Cannabis is a genus of flowering plant within the family Cannabaceae. Cannabis can contain up to 483 known compounds including over 113 known cannabinoids. Our bodies produce cannabinoids endogeously, or internally, called endocannabinoids. These endocannabinoids help to promote general homeostasis. Cannabinoids work by binding directly to cannabinoid receptors within our bodies, the same types of receptors endocannabinoids bind with. At present, there are five recognized cannabinoids produced endogenously throughout the body: Arachidonoylethanolamine (anandamide), 2-arachidonoyl glycerol (2-AG), 2-arachidonyl glyceryl ether (noladin ether), virodhamine, N-arachidonoyl-dopamine (NADA). At least 113 different cannabinoids have been isolated from the Cannabis plant which are also known as phytocannabinoids.
There are at least 2 species within Cannabaceae, Cannabis indica and Cannabis sativa L. with another possible species Cannabis ruderalis under dispute.
The Cannabis indica, is indicative of its short, bushy stature and sedating, narcotic-like highs. Cannabis Indica is typically native to the Hindu Kush Mountains in India, Pakistan, and Afghanistan.
The Cannabis sativa L., indicative of its tall, lanky structure and invigorating, cerebral highs. Cannabis Sativa L. is native to the Central Asia north of the Himalayas but can be found nearly all over the world, except Antartica.
The Cannabis ruderalis, has more in common with Cannabis sativa L. than Cannabis Indica with a tall, lanky structure. What sets it apart is its ability to autoflower which helps in regions where sunlight can last for most of the day and night. Cannabis Ruderalis is native to the Central and Eastern Europe as well as Russia.
The Endocannabinoid System is a group of special receptor within our bodies. Cannabis creates feelings of psychoactivity and euphoria because of the abundance of CB1 receptors mostly located in our brains. Other cannabinoids like Cannabidiol, or CBD, bind with the CB2 receptor. Cannabinoids and the CB1 and CB2 Receptors There are 2 major cannabinoid receptors in our bodies, the CB1 and CB2. Pyschoactive cannabinoids like Delta 9 Tetrahydrocananbinol, or ?9 THC, bind with the CB1 receptor and regulate mood and motivation. Other cannabinoids like Cannabidiol, or CBD, bind with the CB2 receptor which are more abundant.
There are 2 major cannabinoid receptors in our bodies, the CB1 and CB2. Pyschoactive cannabinoids like Delta 9 Tetrahydrocananbinol, or ?9 THC, bind with the CB1 receptor and regulate mood and motivation. Other cannabinoids like Cannabidiol, or CBD, bind with the CB2 receptor which are more abundant throughout the immune system and related organs, such as the tissues of the spleen, tonsils, and thymus gland. They are also common in the brain, although they do not appear as densely as CB1 sites and are found on different types of cells.